ING3 monoclonal antibody (M01), clone 2E9
产品名称: ING3 monoclonal antibody (M01), clone 2E9
英文名称: ING3 monoclonal antibody (M01), clone 2E9
产品编号: H00054556-M01
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ING3.
- Immunogen:
- ING3 (NP_938008, 1 a.a. ~ 92 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLQHF
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.86 KDa) .
- MSDS:
- Download
- Applications
- Western Blot (Cell lysate)
- ING3 monoclonal antibody (M01), clone 2E9. Western Blot analysis of ING3 expression in Hela NE ( Cat # L013V3 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged ING3 is 0.1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 54556
- GeneBank Accession#:
- NM_198267
- Protein Accession#:
- NP_938008
- Gene Name:
- ING3
- Gene Alias:
- Eaf4,FLJ20089,ING2,p47ING3
- Gene Description:
- inhibitor of growth family, member 3
- Omim ID:
- 607493
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq
- Other Designations:
- -
- Related Disease