IL13 monoclonal antibody (M23), clone 3B9
产品名称: IL13 monoclonal antibody (M23), clone 3B9
英文名称: IL13 monoclonal antibody (M23), clone 3B9
产品编号: H00003596-M23
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant IL13.
- Immunogen:
- IL13 (NP_002179, 35 a.a. ~ 146 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MPSPGTVCSLLLLGMLWLDLAMAGSSFLSPEHQRVQQRKESKKPPAKLQPRALAGWLRPEDGGQAEGAEDELEVRFNAPFDVGIKLSGVQYQQHSQALGKFLQDILWEEAKEAPADK
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Application Image
- ELISA
- Entrez GeneID:
- 3596
- GeneBank Accession#:
- NM_002188
- Protein Accession#:
- NP_002179
- Gene Name:
- IL13
- Gene Alias:
- ALRH,BHR1,IL-13,MGC116786,MGC116788,MGC116789,P600
- Gene Description:
- interleukin 13
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq
- Other Designations:
- -
- Related Disease
- Acquired Immunodeficiency Syndrome
- Adenocarcinoma
- Aggressive Periodontitis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Asthma, Exercise-Induced
- Atherosclerosis
- Atherosclerosis
- Biliary Tract Neoplasms
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Calcinosis