ABCC1 monoclonal antibody, clone 33A6
产品名称: ABCC1 monoclonal antibody, clone 33A6
英文名称: ABCC1 monoclonal antibody, clone 33A6
产品编号: MAB3488
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant ABCC1.
- Immunogen:
- Recombinant protein corresponding to cytoplasmic region between transmembrane regions 5 and 6 of human ABCC1.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Recognizes human multidrug resistance-associated protein 1.
- Form:
- Lyophilized
- Isotype:
- IgG2a
- Storage Buffer:
- Lyophilized from tissue culture supernatant (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with distilled water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:25-1:50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Entrez GeneID:
- 4363
- Gene Name:
- ABCC1
- Gene Alias:
- ABC29,ABCC,DKFZp686N04233,DKFZp781G125,GS-X,MRP,MRP1
- Gene Description:
- ATP-binding cassette, sub-family C (CFTR/MRP), member 1
- Omim ID:
- 158343
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. [provided by RefSeq
- Other Designations:
- ATP-binding cassette, sub-family C, member 1,LTC4 transporter,OTTHUMP00000045904,leukotriene C(4) transporter,multidrug resistance protein,multiple drug resistance protein 1,multiple drug resistance-associated protein
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Breast cancer
- Calcinosis
- Carcinoma, Endometrioid
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Colorectal Neoplasms
- Coronary Artery Disease
- Cystadenocarcinoma, Serous
- Cystic Fibrosis
- Cystic fibrosis
- Diabetes Mellitus, Type 2
- Disease Progression
- Drug Toxicity
- Edema