NLRP10 polyclonal antibody
产品名称： NLRP10 polyclonal antibody
英文名称： NLRP10 polyclonal antibody
产品编号： PAB23553
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant NLRP10.
- Immunogen:
- Recombinant protein corresponding to amino acids of human NLRP10.
- Sequence:
- RLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQ
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Isotype:
- IgG
- Storage Buffer:
- In PBS, pH 7.5 (40% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (1:50-1:200)
Western Blot (1:250-1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate), Lane 2: Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells) with NLRP10 polyclonal antibody (Cat # PAB23553) at 1:250-1:500 dilution.
- Entrez GeneID:
- 338322
- Protein Accession#:
- Q86W26
- Gene Name:
- NLRP10
- Gene Alias:
- CLR11.1,NALP10,NOD8,PAN5,PYNOD
- Gene Description:
- NLR family, pyrin domain containing 10
- Omim ID:
- 609662
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq
- Other Designations:
- NACHT, leucine rich repeat and PYD containing 10,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10
- Related Disease