1) Cat. No.: TRC-T445100; 2) Chemical Name: TIQ-A; 3) CAS No.: 420849-22-5; 4) Mol. Formula: C11H7NOS; 5) Mol. Weight: 201.24; 6) Packing Size: 5mg / 50mg; 7) Appearence: Dark Brownish Blue Solid; 8) Application Notes: A cell permeable, potent PARP inhibitor with an IC50 of 450nM.  Shown to be neuroprotective against oxygen-glucose deprivation injury in  vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip).; 9) Synonym: Thieno[2,3-C]isoquinolin-5-one; 10) Solubility: DMSO; 11) Storage condition: -20°C Freezer; 12) References: Chiarugi, A., et al.: J. Pharmacol. Exp. Ther., 305, 43 (2003), pellicciari, R., et al.: Farmaco., 58, 851 (2003)