FITC标记的精子相关抗原17抗体
产品名称： FITC标记的精子相关抗原17抗体
英文名称： Anti-SPAG17/FITC
产品编号： HZ-9596R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SPAG17/FITC Conjugated antibody
FITC标记的精子相关抗原17抗体
| 产品编号 | bs-9596R-FITC |
| 英文名称 | Anti-SPAG17/FITC |
| 中文名称 | FITC标记的精子相关抗原17抗体 |
| 别 名 | PF6; FLJ34497; Projection protein PF6 homolog; RP4 776P7.2; SPAG17; Sperm-associated antigen 17; SPG17_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 252kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPAG17 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: SPAG17 (sperm associated antigen 17), also known as PF6, is a 2,223 amino acid cytoplamic protein that colocalizes with SPAG6 to microtubles. Highly expressed in testis and in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus, SPAG17 may be important for the structural integrity of the central apparatus of the sperm axoneme. SPAG17 contains two LRR (leucine-rich) repeats and may also participate in flagellar motility and male fertility. Function: Seems to be important for the structural integrity of the central apparatus of the sperm axoneme. Subunit: Interacts (via the C-terminus) with SPAG6; the interaction probably occurs on polymerized microtubules (By similarity). Subcellular Location: Cytoplasm. Cytoplasm > cytoskeleton > flagellum axoneme. Detected in the cytoplasm of round spermatids and in condensing spermatids. Localized to the central pair of the sperm flagellar axoneme. Colocalizes with SPAG6 on microtubules. Tissue Specificity: Highly expressed in testis. Expressed in organs that contain cilia-bearing cells including brain, oviduct, lung, and uterus. Database links: Entrez Gene: 200162 Human SwissProt: Q6Q759 Human Unigene: 528821 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
SPAG17（精子相关抗原17），也称为PF6，是一种2223氨基酸的胞质蛋白，与SPAG6共同作用于微管。在含有纤毛的细胞（包括脑、输卵管、肺和子宫）的睾丸和器官中高表达，SPAG17对于精子轴突中心器官的结构完整性可能是重要的。SPAG17包含两个LRR（亮氨酸富集）重复序列，也可能参与鞭毛运动和雄性育性。